Ethical Saving gUG · nonprofit research & innovation

Innovation that improves care.

We develop and support testable solutions for medical and societal challenges — combining research, technology and transparent evidence.

Mission

Turn scientific signals into measurable patient benefit.

Medical innovation begins with a plausible hypothesis and becomes valuable through well-designed studies. We show what mechanism data, preclinical findings and external clinical signals already support, then define the next measurable validation step.

Evidence boundary: AIRCHILL has treated 0 patients. Early feasibility work included healthy volunteers and preclinical models. These data can justify further clinical validation, but they do not prove patient efficacy.
Research questions

Where earlier neuroprotection could matter.

Our current planning covers several time-critical indications. The effect scenarios are transparent sensitivity analyses, not claims of AIRCHILL efficacy.

Cardiac arrest

Earlier temperature control, neuroprotection, timing, safety and neurologically favourable survival.

Stroke

Neuroprotection around thrombectomy and the question whether an additional early intervention can improve functional outcome.

Neonatal HIE

Established therapeutic hypothermia provides a strong biological precedent; any new transport or early-cooling approach requires separate paediatric validation.

Traumatic brain injury

Population selection, intracranial pressure, timing, duration, rewarming and clinically relevant outcomes.

Heatstroke

Cooling speed is critical. A future respiratory approach would need to be evaluated as a complementary option, not as a replacement for established rapid cooling.

Concussion

A separate research field with external head/neck cooling signals; typical concussion is not a current respiratory AIRCHILL use case.

Review sources, assumptions and evidence status →

Public IP

Granted patent family in Europe and the United States.

Public patent records list EP3509683B1 and US11395900B2 and identify Fabian Temme as holder/assignee. The public register view is presented transparently and does not replace formal chain-of-title due diligence.

Projects

Medical technology, diagnostics and open development.

Key projects include Medicalcooling/AIRCHILL, InjuryDetector, GritArmor and open-source software published by Ethical Saving.

EMS reimbursement atlas

District-level German ambulance and emergency physician fee structures, payer logic and primary sources.

Open atlas →

Open Source

Selected software and AI-assisted website infrastructure are published openly.

GitHub organisation →

Emergency care reform 2026

A controlled evaluation and reimbursement pathway for prehospital innovation.

Our current proposal would open the existing German evidence-generation pathway under §137e SGB V to emergency medical services and add a temporary, transport-independent trial reimbursement route under §133 SGB V.

Read the current position paper →

Talk directly.

Book a privacy-conscious 30-minute meeting with Fabian Temme.

Book a meeting →
Support

Help turn promising signals into robust evidence.

Donations support nonprofit research, study preparation, evidence development and project work. They do not guarantee a medical outcome.